Details, Fiction and megatomi.com
Details, Fiction and megatomi.com
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Our new Apparent+ tissue clearing technique is the one technique that delipidates samples without any alter in morphology and with small influence on structural integrity.
Megatome is a vibrating microtome made to segment a broad variety of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With significant blade vibrating frequency and minimized blade deflection, Megatome permits superior-throughput tissue sectioning with uniform surface profile, in addition to minimum tissue hurt and knowledge loss.
Antibodies could get weeks to diffuse by means of just a few millimeters of tissue, which has a steep labeling gradient from area to core.
Megatome is created for precision: the blade vibrates at an increased frequency and bigger amplitude range than other microtomes, and features a unique deflection control mechanism.
SE uses a rotational electric powered field to disperse extremely electromobile molecules (like antibodies or surfactant micelles) throughout a porous sample without the need of harming electrically charged buildings in the tissue. This permits 2-4 working day clearing of intact organs,
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Megatome is often a novel microtome that permits for high-precision sectioning of a wide array of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with nominal tissue injury and knowledge reduction.
eFLASH is a swift tissue labeling approach which allows for uniform complete-organ staining in 20 rounds of labeling.
The SmartSPIM light sheet microscope supplies unparalleled resolution and acquisition speed through intact tissue volumes, whilst its modular style and design enables you to up grade and customize particular person elements.
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SHIELD avoids the variability of hydrogel embedding and the knowledge decline from PFA preservation, guarding specimens for various rounds of processing.
Leverage the Distinct+ tissue clearing strategy, in conjunction with megatomi.com eFLASH and patented stochastic electrotransport systems, to quickly very clear and label complete organs. Critical highlights and features contain:
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